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P-gp inhibitor 1
CAS No. 2050747-49-2
P-gp inhibitor 1 ( —— )
Catalog No. M26354 CAS No. 2050747-49-2
P-gp inhibitor 1 inhibits reversing P-glycoprotein-mediated multidrug resistance with an EC50 of 57.9 nM (K562/A02 cells).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 115 | Get Quote |
|
| 10MG | 192 | Get Quote |
|
| 25MG | 385 | Get Quote |
|
| 50MG | 575 | Get Quote |
|
| 100MG | 801 | Get Quote |
|
| 500MG | 1647 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameP-gp inhibitor 1
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NoteResearch use only, not for human use.
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Brief DescriptionP-gp inhibitor 1 inhibits reversing P-glycoprotein-mediated multidrug resistance with an EC50 of 57.9 nM (K562/A02 cells).
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DescriptionP-gp inhibitor 1 inhibits reversing P-glycoprotein-mediated multidrug resistance with an EC50 of 57.9 nM (K562/A02 cells).(In Vitro):In K562/A02 MDR cells, P-gp inhibitor 1 (0.1, 1, 5 μM, 1 h) boosts the potency of other MDR-related cytotoxic agents with different structures, increases the accumulation of DOX, blocks Pgp-mediated Rh123 efflux, and suppresses P-gp ATPase activity.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorHistamine Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number2050747-49-2
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Formula Weight517.6
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Molecular FormulaC32H31N5O2
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Purity>98% (HPLC)
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Solubility——
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SMILESCOc1cc2CCN(CCc3ccc(Nc4nc(nc5ccccc45)-c4ccncc4)cc3)Cc2cc1OC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Miura M, Uno T. Clinical pharmacokinetics of fexofenadine enantiomers. Expert Opin Drug Metab Toxicol. 2010 Jan;6(1):69-74.
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